Creation of an α-mannosynthase from a broad glycosidase scaffold.

Creation of an α-mannosynthase from a broad glycosidase scaffold.

α-Mannosides made easy: Mutation of a family-GH31 α-glucosidase that displays plasticity to alterations at the 2-OH position of donor substrates created an efficient α-mannoside-synthesizing biocatalyst. A simple fluoride donor reagent was used for the synthesis of a range of mono-α-mannosylated con...

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Autors principals:	Yamamoto, K, Davis, B
Format:	Journal article
Idioma:	English
Publicat:	2012

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