Suppression of the inflammatory response by diphenyleneiodonium after transient focal cerebral ischemia.

Diphenyleneiodonium (DPI), a NADPH oxidase inhibitor, reduces production of reactive oxygen species (ROS) and confers neuroprotection to focal cerebral ischemia. Our objective was to investigate whether the neuroprotective action of DPI extends to averting the immune response. DPI-induced gene chang...

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Bibliographic Details
Main Authors: Nagel, S, Hadley, G, Pfleger, K, Grond-Ginsbach, C, Buchan, A, Wagner, S, Papadakis, M
Format: Journal article
Language:English
Published: 2012