Cavitation-enhanced delivery of a self-amplifying oncolytic adenovirus for tumour-selective cancer therapy.

Unlike conventional gene therapy, oncolytic adenoviruses selectively infect and replicate within cancer cells, potentially enabling systemically administered yet highly targeted self-amplifying cancer therapy. Until recently, therapeutic efficacy was hindered by limited extravasation of the virus to...

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Bibliographic Details
Main Authors: Carlisle, R, Choi, J, Seymour, L, Coussios, C
Format: Conference item
Published: 2012