Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1.

The mechanism of adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channel activation by Mg-nucleotides was studied using a mutation (G334D) in the Kir6.2 subunit of the channel that renders K(ATP) channels insensitive to nucleotide inhibition and has no apparent effect on their gating. K(AT...

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Hlavní autoři: Proks, P, De Wet, H, Ashcroft, F
Médium: Journal article
Jazyk:English
Vydáno: 2010