Inhibition of alpha-glucosidases I and II increases the cell surface expression of functional class A macrophage scavenger receptor (SR-A) by extending its half-life.

Inhibition of alpha-glucosidases I and II increases the cell surface expression of functional class A macrophage scavenger receptor (SR-A) by extending its half-life.

The class A scavenger receptor (SR-A) is a multifunctional trimeric membrane glycoprotein involved in atherogenesis. The mature receptor can mediate the binding and internalization of a number of specific ligands, including modified low-density lipoprotein. We have investigated the effects of inhibi...

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Dettagli Bibliografici
Autori principali:	Tian, G, Wilcockson, D, Perry, V, Rudd, P, Dwek, R, Platt, F, Platt, N
Natura:	Journal article
Lingua:	English
Pubblicazione:	2004

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