Characterizing the free-energy landscapes of DNA origamis

We show how coarse-grained modelling combined with umbrella sampling using distance-based order parameters can be applied to compute the free-energy landscapes associated with mechanical deformations of large DNA nanostructures. We illustrate this approach for the strong bending of DNA nanotubes and...

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Detaylı Bibliyografya
Asıl Yazarlar: Wong, CK, Tang, C, Schreck, JS, Doye, JPK
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2022