Development of a versatile oncolytic virus platform for local intra-tumoural expression of therapeutic transgenes
Oncolytic viruses which infect and kill tumour cells can also be genetically modified to express therapeutic genes that augment their anti-cancer activities. Modifying oncolytic viruses to produce effective cancer therapies is challenging as encoding transgenes often attenuates virus activity or pre...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Published: |
Public Library of Science
2017
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