Inhibition of ATP-regulated K(+)-channels by a photoactivatable ATP-analogue in mouse pancreatic beta-cells.

The effects of a photoactivable (DMNPE-caged) ATP-analogue on ATP-regulated K(+)-channels (KATP-channel) in mouse pancreatic beta-cells were investigated using the inside-out patch configuration of the patch-clamp technique. The caged precursor caused a concentration-dependent reduction of channel a...

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Bibliografiske detaljer
Main Authors: Ammälä, C, Bokvist, K, Galt, S, Rorsman, P
Format: Journal article
Sprog:English
Udgivet: 1991