Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression

RNA polymerase II (Pol II) transcribes genes that encode proteins and noncoding small nuclear RNAs (snRNAs). The carboxyl-terminal repeat domain (CTD) of the largest subunit of mammalian RNA Pol II, comprising tandem repeats of the heptapeptide consensus Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7, is requir...

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Bibliographic Details
Main Authors: Egloff, S, O'Reilly, D, Chapman, R, Taylor, A, Tanzhaus, K, Pitts, L, Eick, D, Murphy, S
Format: Journal article
Language:English
Published: American Association for the Advancement of Science 2007