mRNA cap methyltransferase, RNMT-RAM, promotes RNA Pol II-dependent transcription
mRNA cap addition occurs early during RNA Pol II-dependent transcription, facilitating pre-mRNA processing and translation. We report that the mammalian mRNA cap methyltransferase, RNMT-RAM, promotes RNA Pol II transcription independent of mRNA capping and translation. In cells, sublethal suppressio...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Published: |
Elsevier
2018
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