Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.

The initiation and progression of breast cancer from the transformation of the normal epithelium to ductal carcinoma in situ (DCIS) and invasive disease is a complex process involving the acquisition of genetic alterations and changes in gene expression, alongside microenvironmental and recognized h...

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Bibliographic Details
Main Authors: Maguire, S, Peck, B, Wai, P, Campbell, J, Barker, H, Gulati, A, Daley, F, Vyse, S, Huang, P, Lord, C, Farnie, G, Brennan, K, Natrajan, R
Format: Journal article
Language:English
Published: Wiley 2016