The pharmacological profile of a novel highly potent bisphosphonate, OX14 (1-Fluoro-2-(Imidazo-[1,2-α]Pyridin-3-yl)-Ethyl-Bisphosphonate)

Bisphosphonates are widely used in the treatment of clinical disorders characterized by increased bone resorption, including osteoporosis, Paget's disease, and the skeletal complications of malignancy. The antiresorptive potency of the nitrogen-containing bisphosphonates on bone in vivo is now...

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Main Authors: Lawson, M, Ebetino, F, Mazur, A, Chantry, A, Paton-Hough, J, Evans, H, Lath, D, Tsoumpra, M, Lundy, M, Dobson, R, Quijano, M, Kwaasi, A, Dunford, J, Duan, X, Triffitt, J, Jeans, G, Russell, R
Format: Journal article
Language:English
Published: American Society for Bone and Mineral Research 2017