Interaction of vanadate with the cloned beta cell K(ATP) channel.

Vanadate is used as a tool to trap magnesium nucleotides in the catalytic site of ATPases. However, it has also been reported to activate ATP-sensitive potassium (K(ATP)) channels in the absence of nucleotides. K(ATP) channels comprise Kir6.2 and sulfonylurea receptor subunits (SUR1 in pancreatic be...

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Bibliografische gegevens
Hoofdauteurs: Proks, P, Ashfield, R, Ashcroft, F
Formaat: Journal article
Taal:English
Gepubliceerd in: 1999