Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses.

Macrophages are reservoirs of HIV-1 infection, proposed to transmit virus to CD4(+) T cells, the primary target of the virus. Here we report that human monocyte-derived macrophages (MDMs) rapidly spread HIV-1 to autologous CD4(+) T cells resulting in productive infection. Transmission takes place ac...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Groot, F, Welsch, S, Sattentau, Q
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2008