Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo.

Dendritic cells (DC) were cultured from mouse bone marrow (BM) progenitors in low concentrations of granulocyte-macrophage colony-stimulating factor (GM-CSF) (GM(lo) DC) by two different protocols. The phenotype and functional properties of these GM(lo) DC were compared to those of standard BM-DC cu...

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Bibliographic Details
Main Authors: Lutz, M, Suri, R, Niimi, M, Ogilvie, A, Kukutsch, N, Rössner, S, Schuler, G, Austyn, J
Format: Journal article
Language:English
Published: 2000