Syntheses of (6S)-cephalosporins from 6-aminopenicillanic acid

Two practical routes to (6S,7S)-cephalosporins from 6-aminopenicillanic acid (6-APA) are described. In the first, 6-APA was converted to (2S,4S,5S,6S)-penicillin sulfoxide 49, which underwent Morin ring expansion to a protected (6S,7S)-cephem 50. In the second, ester 15 was converted to (2S,4S,5S,6R...

詳細記述

書誌詳細
主要な著者: Fekner, T, Baldwin, J, Adlington, R, Jones, T, Prout, C, Schofield, C
フォーマット: Journal article
言語:English
出版事項: 2000