Syntheses of (6S)-cephalosporins from 6-aminopenicillanic acid

Syntheses of (6S)-cephalosporins from 6-aminopenicillanic acid

Two practical routes to (6S,7S)-cephalosporins from 6-aminopenicillanic acid (6-APA) are described. In the first, 6-APA was converted to (2S,4S,5S,6S)-penicillin sulfoxide 49, which underwent Morin ring expansion to a protected (6S,7S)-cephem 50. In the second, ester 15 was converted to (2S,4S,5S,6R...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Fekner, T, Baldwin, J, Adlington, R, Jones, T, Prout, C, Schofield, C
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2000

समान संसाधन

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प्रकाशित: (1996)

Acyl coenzyme A: 6-aminopenicillanic acid acyltransferase from Penicillium chrysogenum and Aspergillus nidulans.
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Enzymatic acylation of 6-aminopenicillanic acid /
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THE ENZYMATIC CONVERSION OF EXOMETHYLENE CEPHALOSPORIN-C INTO DEACETYL CEPHALOSPORIN-C AND THE ROLE OF MOLECULAR-OXYGEN IN CEPHALOSPORIN-C BIOSYNTHESIS
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Spectrophotometric method for the estimation of 6-Aminopenicillanic acid /
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6- Aminopenicillanic acid by immobilised penicillin acylase /
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Unusually stable azetidinone sulfenic acids
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Evaluation of determination of 6-aminopenicillanic acid by p-dimethyl aminobenzaldehyde /
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Production of 6-Aminopenicillanic Acid with immobilized Escherichia coli Acylase /
द्वारा: Largerlof, E.

THE ROLE OF ALPHA-KETOGLUTARATE IN CEPHALOSPORIN BIOSYNTHESIS
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THE ROLE OF MOLECULAR-OXYGEN IN CEPHALOSPORIN-C BIOSYNTHESIS
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प्रकाशित: (1987)

Laccase-catalyzed derivatization of 6-aminopenicillanic, 7-aminocephalosporanic and 7-aminodesacetoxycephalosporanic acid
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CEPHALOSPORIN BIOSYNTHESIS - A BRANCHED PATHWAY SENSITIVE TO AN ISOTOPE EFFECT
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Performance of the recirculated packed bed reactor for the hydrolysis of penicillin G to 6-aminopenicillanic acid /
द्वारा: Lee, Chew Tin 501000, और अन्य

THE ENZYMATIC RING EXPANSION OF PENICILLINS TO CEPHALOSPORINS - SIDE-CHAIN SPECIFICITY
द्वारा: Baldwin, J, और अन्य
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CLEAVAGE OF THE 5-AMINO-5-CARBOXY-2-OXAPENTANOYL SIDE-CHAIN FROM ENZYMATICALLY SYNTHESIZED PENICILLINS AND CEPHALOSPORINS
द्वारा: Baldwin, J, और अन्य
प्रकाशित: (1995)

Modeling for the hydrolysis of penicillin G to 6-aminopenicillanic acid using computer program ENZSIM2000 /
द्वारा: 191562 Wong, Tak Hiong, और अन्य
प्रकाशित: (2001)

CEPHALOSPORIN-C BIOSYNTHESIS - A BRANCHED PATHWAY SENSITIVE TO A KINETIC ISOTOPE EFFECT
द्वारा: Baldwin, J, और अन्य
प्रकाशित: (1987)

ENZYMATIC RING EXPANSION OF PENICILLINS TO CEPHALOSPORINS - SIDE-CHAIN SPECIFICITY
द्वारा: Baldwin, J, और अन्य
प्रकाशित: (1987)

Separation of phenyl acetic acid and 6-aminopenicillanic acid applying aqueous two-phase systems based on copolymers and salts
द्वारा: Farzaneh Ghazizadeh Ahsaie, और अन्य
प्रकाशित: (2021-02-01)

Kinetic model of the recirculated packed bed immobilized enzyme reactor for the hydrolysis of penicillin G to 6-aminopenicillanic acid /
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प्रकाशित: (2000)

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प्रकाशित: (1989)

CEPHALOSPORIN-C BIOSYNTHESIS - STEREOCHEMISTRY OF THE INCORPORATION OF D,L,D-ALPHA-AMINODIPOYL-CYSTEINYL-(3S)-[2-2H,4-C-13]VALINE INTO BETA-LACTAM COMPOUNDS
द्वारा: Baldwin, J, और अन्य
प्रकाशित: (1989)

STUDIES ON THE MECHANISM OF DEACETOXY DEACETYLCEPHALOSPORIN-C SYNTHASE USING CYCLOPROPYL SUBSTITUTED CEPHALOSPORIN PROBES
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Pemodelan reaktor lapisan terpadat edaran-berulangan berkelompok untuk hidrolisis penicilin-g kepada 6-aminopenicillanic acid /
द्वारा: 463344 Lai, Kok Chean
प्रकाशित: (1999)

THE ROLE OF SULFUR IN CEPHALOSPORIN BIOSYNTHESIS
द्वारा: Baldwin, J, और अन्य
प्रकाशित: (1991)

Process Development for 6‑Aminopenicillanic Acid Production Using Lentikats-Encapsulated Escherichia coli Cells Expressing Penicillin V Acylase
द्वारा: Amol M. Sawant, और अन्य
प्रकाशित: (2020-11-01)

Correction to “Process Development for 6‑Aminopenicillanic Acid Production Using Lentikats-Encapsulated Escherichia coli Cells Expressing Penicillin V Acylase”
द्वारा: Amol M. Sawant, और अन्य
प्रकाशित: (2024-06-01)

Hydrolysis of penicillin G to 6-aminopenicillanic acid in a batch stirred-tank reactor and a recirculated packed bed batch reactor /
द्वारा: Lee, Chew Tin 501000
प्रकाशित: (1998)

Ionic strength and PH effects in the kinetically controlled synthesis of benzylpenicillin by nucleophilic deacylation of free and immobilized phenyl-acetyl-penicillin amidase with 6-aminopenicillanic acid/
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द्वारा: Baldwin, J, और अन्य
प्रकाशित: (1985)

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GAMMA-LACTAM ANALOGS OF CARBAPENICILLANIC ACIDS
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प्रकाशित: (1998)

SYNTHESES OF CIS-PYRROLIDINE-2 AND TRANS-PYRROLIDINE-2,5-DICARBOXYLIC ACIDS
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Synthesis and biological activity study of some novel Tri-Schiff’s basses derived from 6-aminopenicillanic acid and Tri-amide containing three 1,3,4-thiadiazole units.
द्वारा: Radwan M. Ali Hameed
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Syntheses of (S)-beta-pyrazolylalanine and (S)-quisqualic acid from a serine-derived aziridine
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