A large deletion in the human alpha-globin cluster caused by a replication error is associated with an unexpectedly mild phenotype.
We have characterized a newly identified 16.6 kb deletion which removes a significant proportion of the human alpha-globin cluster including the psizeta1, alpha(D), psialpha1 and alpha2-globin genes but leaves the duplicated alpha1 gene intact. This complicated rearrangement results from a combinati...
Հիմնական հեղինակներ: | Rugless, M, Fisher, C, Old, J, Sloane-Stanley, J, Ayyub, H, Higgs, D, Garrick, D |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2008
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Deletion of the mouse alpha globin regulatory element (HS-26) has an unexpectedly mild phenotype.
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