Galectin-3 is an amplifier of inflammation in atherosclerotic plaque progression through macrophage activation and monocyte chemoattraction.
OBJECTIVE: Galectin-3 (Gal-3) is a 26-kDa lectin known to regulate many aspects of inflammatory cell behavior. We assessed the hypothesis that increased levels of Gal-3 contribute to atherosclerotic plaque progression by enhancing monocyte chemoattraction through macrophage activation. METHODS AND...
Huvudupphovsmän: | Papaspyridonos, M, McNeill, E, de Bono, J, Smith, A, Burnand, K, Channon, K, Greaves, D |
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Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
2008
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