A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA

Extracellular vesicles (EVs) form an endogenous transport system for intercellular transfer of biological cargo, including RNA, that plays a pivotal role in physiological and pathological processes. Unfortunately, whereas biological effects of EV-mediated RNA transfer are abundantly studied, regulat...

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Bibliographic Details
Main Authors: de Jong, OG, Murphy, DE, Mager, I, Willms, E, Garcia-Guerra, A, Gitz-Francois, JJ, Lefferts, J, Gupta, D, Steenbeek, SC, van Rheenen, J, El-Andaloussi, S, Schiffelers, RM, Wood, MJA, Vader, P
Format: Journal article
Language:English
Published: Springer Nature 2020
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