Allelic diversity and naturally acquired allele-specific antibody responses to Plasmodium falciparum apical membrane antigen 1 in Kenya.

Although Plasmodium falciparum apical membrane antigen 1 (AMA1) is a leading malaria vaccine candidate, extensive allelic diversity may compromise its vaccine potential. We have previously shown that naturally acquired antibodies to AMA1 were associated with protection from clinical malaria in this...

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Bibliographic Details
Main Authors: Osier, F, Weedall, G, Verra, F, Murungi, L, Tetteh, K, Bull, P, Faber, B, Remarque, E, Thomas, A, Marsh, K, Conway, D
Format: Journal article
Language:English
Published: 2010