Impact of depleting therapeutic monoclonal antibodies on the host adaptive immunity: a bonus or a malus?

Clinical responses to anti-tumor monoclonal antibody (mAb) treatment have been regarded for many years only as a consequence of the ability of mAbs to destroy tumor cells by innate immune effector mechanisms. More recently, it has also been shown that anti-tumor antibodies can induce a long-lasting...

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Bibliographic Details
Main Authors: Deligne, C, Milcent, B, Josseaume, N, Teillaud, J, Sibéril, S
Format: Journal article
Language:English
Published: Frontiers Media 2017