Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.

Hypoxia results in adaptive changes in the transcription of a range of genes including erythropoietin. An important mediator is hypoxia-inducible factor-1 (HIF-1), a DNA binding complex shown to contain at least two basic helix-loop-helix PAS-domain (bHLH-PAS) proteins, HIF-1alpha and aryl hydrocarb...

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Bibliographic Details
Main Authors:	Wiesener, MS, Turley, H, Allen, W, Willam, C, Eckardt, K, Talks, K, Wood, S, Gatter, K, Harris, A, Pugh, C, Ratcliffe, P, Maxwell, P
Format:	Journal article
Language:	English
Published:	1998

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.

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