Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.

Hypoxia results in adaptive changes in the transcription of a range of genes including erythropoietin. An important mediator is hypoxia-inducible factor-1 (HIF-1), a DNA binding complex shown to contain at least two basic helix-loop-helix PAS-domain (bHLH-PAS) proteins, HIF-1alpha and aryl hydrocarb...

Bibliografske podrobnosti
Main Authors:	Wiesener, MS, Turley, H, Allen, W, Willam, C, Eckardt, K, Talks, K, Wood, S, Gatter, K, Harris, A, Pugh, C, Ratcliffe, P, Maxwell, P
Format:	Journal article
Jezik:	English
Izdano:	1998

Podobne knjige/članki

The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages.
od: Talks, K, et al.
Izdano: (2000)

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression.
od: Wood, S, et al.
Izdano: (1998)

Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha.
od: O'Rourke, J, et al.
Izdano: (1999)

Expression of hypoxia-inducible factors-1alpha and-2alpha in hypoxic and ischemic rat kidneys
od: Rosenberger, C, et al.
Izdano: (2002)

Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys.
od: Rosenberger, C, et al.
Izdano: (2002)

The prolyl hydroxylase enzymes that act as oxygen sensors regulating destruction of hypoxia-inducible factor alpha.
od: Willam, C, et al.
Izdano: (2004)

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation.
od: Masson, N, et al.
Izdano: (2001)

HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation.
od: Willam, C, et al.
Izdano: (2006)

Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival.
od: Giatromanolaki, A, et al.
Izdano: (2001)

Regulation of the Drosophila bHLH-PAS protein Sima by hypoxia: functional evidence for homology with mammalian HIF-1 alpha.
od: Bacon, N, et al.
Izdano: (1998)

Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.
od: Wiesener, MS, et al.
Izdano: (2003)

Hypoxia-inducible expression of tumor-associated carbonic anhydrases.
od: Wykoff, C, et al.
Izdano: (2000)

Expression of angiogenic factors and hypoxia inducible factors HIF 1, HIF 2 and CA IX in non-Hodgkin's lymphoma.
od: Stewart, M, et al.
Izdano: (2002)

Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival.
od: Hui, E, et al.
Izdano: (2002)

CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia-inducible factor 1alpha.
od: Fox, S, et al.
Izdano: (2004)

Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer.
od: Koukourakis, M, et al.
Izdano: (2002)

Hypoxia inducible factor 1alpha and 2alpha overexpression in inflammatory bowel disease.
od: Giatromanolaki, A, et al.
Izdano: (2003)

Hypoxia-inducible factors 1alpha and 2alpha are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin.
od: Giatromanolaki, A, et al.
Izdano: (2003)

Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis.
od: Rasheed, S, et al.
Izdano: (2009)

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.
od: Tian, Y, et al.
Izdano: (2011)

Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer.
od: Leek, R, et al.
Izdano: (2002)

Activation of hypoxia-inducible factor-1; definition of regulatory domains within the alpha subunit.
od: Pugh, C, et al.
Izdano: (1997)

Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.
od: Sowter, H, et al.
Izdano: (2003)

Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression.
od: Ratcliffe, P, et al.
Izdano: (1998)

Hypoxia response elements.
od: O'Rourke, J, et al.
Izdano: (1997)

Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas.
od: Giatromanolaki, A, et al.
Izdano: (2006)

DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer.
od: Giatromanolaki, A, et al.
Izdano: (2003)

Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues.
od: Soilleux, E, et al.
Izdano: (2005)

The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in human tissues and tumours.
od: Turley, H, et al.
Izdano: (2004)

Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density.
od: Beasley, N, et al.
Izdano: (2001)

Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis.
od: Giatromanolaki, A, et al.
Izdano: (2003)

Association of hypoxia-inducible factors 1alpha and 2alpha with activated angiogenic pathways and prognosis in patients with endometrial carcinoma.
od: Sivridis, E, et al.
Izdano: (2002)

New horizons in hypoxia signaling pathways
od: Pugh, C, et al.
Izdano: (2017)

Hypoxia and oxidative stress in breast cancer. Hypoxia signalling pathways.
od: Pugh, C, et al.
Izdano: (2001)

The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis.
od: Pugh, C, et al.
Izdano: (2003)

Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha.
od: Elkins, J, et al.
Izdano: (2003)

Mammalian oxygen sensing and hypoxia inducible factor-1
od: Wood, S, et al.
Izdano: (1997)

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
od: Appelhoff, R, et al.
Izdano: (2004)

Regulation of angiogenesis by hypoxia: role of the HIF system.
od: Pugh, C, et al.
Izdano: (2003)

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.
od: Maxwell, P, et al.
Izdano: (1999)