Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis

Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis

Rheumatoid arthritis affects individuals commonly during the most productive years of adulthood. Poor response rates and high costs associated with treatment mandate the search for new therapies. Here we show that targeting a specific G-protein coupled receptor promotes senescence in synovial fibrob...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Montero-Melendez, T, Nagano, A, Chelala, C, Filer, A, Buckley, CD, Perretti, M
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Nature Research 2020

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