A humanized CD18 antibody can block function without cell destruction.

Leukocyte integrins are intimately involved in transient adherence of leukocytes to endothelium and to each other in the processes of extravasation and cell activation. In this study, seven mAb directed against human CD11a and two mAb directed against human CD18, the alpha- and beta-chains of the le...

Full description

Bibliographic Details
Main Authors: Sims, M, Hassal, D, Brett, S, Rowan, W, Lockyer, M, Angel, A, Lewis, A, Hale, G, Waldmann, H, Crowe, J
Format: Journal article
Language:English
Published: 1993