A global profile of replicative polymerase usage.

Three eukaryotic DNA polymerases are essential for genome replication. Polymerase (Pol) α-primase initiates each synthesis event and is rapidly replaced by processive DNA polymerases: Polɛ replicates the leading strand, whereas Polδ performs lagging-strand synthesis. However, it is not known whether...

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Bibliographic Details
Main Authors: Daigaku, Y, Keszthelyi, A, Müller, C, Miyabe, I, Brooks, T, Retkute, R, Hubank, M, Nieduszynski, C, Carr, A
Format: Journal article
Language:English
Published: Springer Nature 2015