A global profile of replicative polymerase usage.
Three eukaryotic DNA polymerases are essential for genome replication. Polymerase (Pol) α-primase initiates each synthesis event and is rapidly replaced by processive DNA polymerases: Polɛ replicates the leading strand, whereas Polδ performs lagging-strand synthesis. However, it is not known whether...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2015
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