Radiosensitation in vivo by histone deacetylase inhibition with no increase in early normal tissue radiation toxicity

As the population ages, more elderly patients require radiotherapy-based treatment for their pelvic malignancies, including muscle-invasive bladder cancer, as they are unfit for major surgery. Therefore, there is an urgent need to find radiosensitising agents minimally toxic to normal tissues, inclu...

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Bibliographic Details
Main Authors: Groselj, B, Ruan, J, Scott, H, Gorrill, J, Nicholson, J, Kelly, J, Anbalagan, S, Thompson, J, Stratford, M, Jevons, S, Hammond, E, Scudamore, C, Kerr, M, Kiltie, A
Format: Journal article
Published: American Association for Cancer Research 2017