Notch signalling drives synovial fibroblast identity and arthritis pathology
The synovium is a mesenchymal tissue composed mainly of fibroblasts, with a lining and sublining that surround the joints. In rheumatoid arthritis the synovial tissue undergoes marked hyperplasia, becomes inflamed and invasive, and destroys the joint. It has recently been shown that a subset of fibr...
Главные авторы: | , , , , , , , , , , , , , , , , , |
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Другие авторы: | |
Формат: | Journal article |
Язык: | English |
Опубликовано: |
Springer Nature
2020
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