Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT 2A receptors: functional receptor-binding and in vivo electrophysiological studies.

BACKGROUND: Aripiprazole (7-{4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy}-3,4-dihydro-2(1H)-quinolinone) is a novel antipsychotic with a mechanism of action that differs from current typical and atypical antipsychotics. Aripiprazole interacts with a range of receptors, including serotonin [5-hyd...

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Bibliographic Details
Main Authors: Stark, A, Jordan, S, Allers, K, Bertekap, R, Chen, R, Mistry Kannan, T, Molski, T, Yocca, F, Sharp, T, Kikuchi, T, Burris, K
Format: Journal article
Language:English
Published: 2007