Hypoxia imaging using PET and SPECT: the effects of anesthetic and carrier gas on [Cu]-ATSM, [Tc]-HL91 and [F]-FMISO tumor hypoxia accumulation.

Preclinical imaging requires anaesthesia to reduce motion-related artefacts. For direct translational relevance, anaesthesia must not significantly alter experimental outcome. This study reports on the effects of both anaesthetic and carrier gas upon the uptake of [$^64$Cu]-CuATSM, [($^99$m)Tc]-HL91...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Kersemans, V, Cornelissen, B, Hueting, R, Tredwell, M, Hussien, K, Allen, P, Falzone, N, Hill, S, Dilworth, J, Gouverneur, V, Muschel, R, Smart, V
Format: Journal article
Sprache:English
Veröffentlicht: Public Library of Science 2011