Uptake of branched polypeptides with poly[L-lys] backbone by bone-marrow culture-derived murine macrophages: the role of the class a scavenger receptor.

Selective delivery of antiparasitic or antibacterial drugs into infected macrophages could be a promising approach for improved therapies. Methotrexate conjugate with branched chain polypeptides exhibited pronounced anti-Leishmania activity in vitro and in vivo as reported here earlier. To identify...

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Bibliographic Details
Main Authors: Szabó, R, Peiser, L, Plüddemann, A, Bösze, S, Heinsbroek, S, Gordon, S, Hudecz, F
Format: Journal article
Language:English
Published: 2005