Desymmetrization by direct cross-metathesis producing hitherto unreachable P-stereogenic phosphine oxides
Desymmetrization of prochiral di- and trialkenyl phosphine oxides by cross-metathesis with various olefinic partners allowed direct access to novel racemic P-stereogenic products featuring two or three different alkenyl groups. The excellent control of product selectivity and E/Z selectivity allowed...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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2005
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| _version_ | 1797066418661883904 |
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| author | Bisaro, F Gouverneur, V |
| author_facet | Bisaro, F Gouverneur, V |
| author_sort | Bisaro, F |
| collection | OXFORD |
| description | Desymmetrization of prochiral di- and trialkenyl phosphine oxides by cross-metathesis with various olefinic partners allowed direct access to novel racemic P-stereogenic products featuring two or three different alkenyl groups. The excellent control of product selectivity and E/Z selectivity allowed the preparation of desymmetrized products in good yields from readily available precursors. These are the first examples of desymmetrization of prochiral substrates by direct cross-metathesis. © 2005 Elsevier Ltd. All rights reserved. |
| first_indexed | 2024-03-06T21:41:47Z |
| format | Journal article |
| id | oxford-uuid:482d7e1c-523d-4cfb-837b-7e5c39cd3304 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:41:47Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:482d7e1c-523d-4cfb-837b-7e5c39cd33042022-03-26T15:24:12ZDesymmetrization by direct cross-metathesis producing hitherto unreachable P-stereogenic phosphine oxidesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:482d7e1c-523d-4cfb-837b-7e5c39cd3304EnglishSymplectic Elements at Oxford2005Bisaro, FGouverneur, VDesymmetrization of prochiral di- and trialkenyl phosphine oxides by cross-metathesis with various olefinic partners allowed direct access to novel racemic P-stereogenic products featuring two or three different alkenyl groups. The excellent control of product selectivity and E/Z selectivity allowed the preparation of desymmetrized products in good yields from readily available precursors. These are the first examples of desymmetrization of prochiral substrates by direct cross-metathesis. © 2005 Elsevier Ltd. All rights reserved. |
| spellingShingle | Bisaro, F Gouverneur, V Desymmetrization by direct cross-metathesis producing hitherto unreachable P-stereogenic phosphine oxides |
| title | Desymmetrization by direct cross-metathesis producing hitherto unreachable P-stereogenic phosphine oxides |
| title_full | Desymmetrization by direct cross-metathesis producing hitherto unreachable P-stereogenic phosphine oxides |
| title_fullStr | Desymmetrization by direct cross-metathesis producing hitherto unreachable P-stereogenic phosphine oxides |
| title_full_unstemmed | Desymmetrization by direct cross-metathesis producing hitherto unreachable P-stereogenic phosphine oxides |
| title_short | Desymmetrization by direct cross-metathesis producing hitherto unreachable P-stereogenic phosphine oxides |
| title_sort | desymmetrization by direct cross metathesis producing hitherto unreachable p stereogenic phosphine oxides |
| work_keys_str_mv | AT bisarof desymmetrizationbydirectcrossmetathesisproducinghithertounreachablepstereogenicphosphineoxides AT gouverneurv desymmetrizationbydirectcrossmetathesisproducinghithertounreachablepstereogenicphosphineoxides |