Evolution of the Alx homeobox gene family: parallel retention and independent loss of the vertebrate Alx3 gene.

The Alx gene family is implicated in craniofacial development and comprises two to four homeobox genes in each vertebrate genome analyzed. Using phylogenetics and comparative genomics, we show that the common ancestor of jawed vertebrates had three Alx genes descendent from the two-round genome dupl...

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Bibliographic Details
Main Authors: McGonnell, I, Graham, A, Richardson, J, Fish, J, Depew, M, Dee, C, Holland, P, Takahashi, T
Format: Journal article
Language:English
Published: 2011