FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.

FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.

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Accumulation of the DNA/RNA binding protein fused in sarcoma as cytoplasmic inclusions in neurons and glial cells is the pathological hallmark of all patients with amyotrophic lateral sclerosis with mutations in FUS as well as in several subtypes of frontotemporal lobar degeneration, which are not a...

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Bibliographic Details
Main Authors: Neumann, M, Bentmann, E, Dormann, D, Jawaid, A, DeJesus-Hernandez, M, Ansorge, O, Roeber, S, Kretzschmar, H, Munoz, D, Kusaka, H, Yokota, O, Ang, L, Bilbao, J, Rademakers, R, Haass, C, Mackenzie, I
Format: Journal article
Language:English
Published: 2011

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