FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.
Accumulation of the DNA/RNA binding protein fused in sarcoma as cytoplasmic inclusions in neurons and glial cells is the pathological hallmark of all patients with amyotrophic lateral sclerosis with mutations in FUS as well as in several subtypes of frontotemporal lobar degeneration, which are not a...
Main Authors: | Neumann, M, Bentmann, E, Dormann, D, Jawaid, A, DeJesus-Hernandez, M, Ansorge, O, Roeber, S, Kretzschmar, H, Munoz, D, Kusaka, H, Yokota, O, Ang, L, Bilbao, J, Rademakers, R, Haass, C, Mackenzie, I |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2011
|
Similar Items
-
FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations
by: Neumann, M, et al.
Published: (2011) -
Importance of Functional Loss of FUS in FTLD/ALS
by: Shinsuke Ishigaki, et al.
Published: (2018-05-01) -
Gene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions.
by: Jenny Blechingberg, et al.
Published: (2012-01-01) -
Neuroimaging-guided diagnosis of possible FTLD-FUS pathology: a case report
by: Gregory Mathoux, et al.
Published: (2024-04-01) -
Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS
by: Lauren M. Gittings, et al.
Published: (2019-02-01)