Advances in the 5q- syndrome.

Advances in the 5q- syndrome.

The 5q- syndrome is the most distinct of all the myelodysplastic syndromes with a clear genotype/phenotype relationship. The significant progress made during recent years has been based on the determination of the commonly deleted region and the demonstration of haploinsufficiency for the ribosomal...

Podrobná bibliografie
Hlavní autoři:	Boultwood, J, Pellagatti, A, McKenzie, A, Wainscoat, J
Médium:	Journal article
Jazyk:	English
Vydáno:	2010

Podobné jednotky

5q- syndrome.
Autor: Boultwood, J, a další
Vydáno: (2012)

RECENT ADVANCES IN THE 5Q- SYNDROME
Autor: Andrea Pellagatti, a další
Vydáno: (2015-05-01)

Haploinsufficiency of ribosomal proteins and p53 activation in anemia: Diamond-Blackfan anemia and the 5q- syndrome.
Autor: Boultwood, J, a další
Vydáno: (2012)

The 5q-syndrome.
Autor: Boultwood, J, a další
Vydáno: (1994)

Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome.
Autor: Pellagatti, A, a další
Vydáno: (2010)

Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies.
Autor: Boultwood, J, a další
Vydáno: (2013)

The 5q- syndrome.
Autor: Giagounidis, A, a další
Vydáno: (2004)

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome.
Autor: Pellagatti, A, a další
Vydáno: (2011)

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome
Autor: Pellagatti, A, a další
Vydáno: (2011)

Gene expression profiling in 5q-syndrome and myelodysplastic syndromes.
Autor: Pellagatti, A, a další
Vydáno: (2003)

MOLECULAR DELINEATION OF THE CRITICAL REGION OF THE 5Q-CHROMOSOME IN THE 5Q-SYNDROME
Autor: Boultwood, J, a další
Vydáno: (1993)

The human POP2 gene: identification, sequencing, and mapping to the critical region of the 5q- syndrome.
Autor: Fidler, C, a další
Vydáno: (1999)

Expression profiling of CD34+cells in patients with myelodysplastic syndromes with and without a del(5q)
Autor: Pellagatti, A, a další
Vydáno: (2005)

Lenalidomide selectively inhibits in vitro growth of the malignant clone in myelodysplastic syndrome (MDS) patients with 5q deletion.
Autor: Jadersten, M, a další
Vydáno: (2005)

Molecular mapping of uncharacteristically small 5q deletions in two patients with the 5q- syndrome: delineation of the critical region on 5q and identification of a 5q- breakpoint.
Autor: Boultwood, J, a další
Vydáno: (1994)

MOLECULAR MAPPING OF UNCHARACTERISTICALLY SMALL 5Q DELETIONS IN 2 PATIENTS WITH THE 5Q- SYNDROME - DELINEATION OF THE CRITICAL REGION ON 5Q AND IDENTIFICATION OF A 5Q- BREAKPOINT
Autor: Boultwood, J, a další
Vydáno: (1993)

Gene expression profiling in the myelodysplastic syndromes.
Autor: Pellagatti, A, a další
Vydáno: (2005)

Effects of L-leucine in 5q-syndrome and other RPS14-deficient erythroblasts
Autor: Yip, B, a další
Vydáno: (2012)

Effects of L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.
Autor: Yip, B, a další
Vydáno: (2012)

Expression profiling of CD34+cells in patients with myelodysplastic syndromes with and without a del(5q).
Autor: Pellagatti, A, a další
Vydáno: (2004)

Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression.
Autor: Jädersten, M, a další
Vydáno: (2009)

SF3B1 mutant myelodysplastic syndrome: Recent advances
Autor: Pellagatti, A, a další
Vydáno: (2020)

ISOLATION OF NOVEL CDNA CLONES MAPPING TO THE CRITICAL REGION OF THE 5Q-CHROMOSOME IN THE 5Q-SYNDROME
Autor: Boultwood, J, a další
Vydáno: (1994)

Homozygous deletion of FMS in a patient with the 5q- syndrome.
Autor: Boultwood, J, a další
Vydáno: (1990)

Narrowing and genomic annotation of the critical region of the 5q-syndrome.
Autor: Boultwood, J, a další
Vydáno: (2000)

Gene expression profiling of CD34+ cells in patients with the 5q- syndrome.
Autor: Boultwood, J, a další
Vydáno: (2007)

Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes.
Autor: Pellagatti, A, a další
Vydáno: (2008)

Physical mapping of the human ATX1 homologue (HAH1) to the critical region of the 5q- syndrome within 5q32, and immediately adjacent to the SPARC gene.
Autor: Boultwood, J, a další
Vydáno: (2000)

Molecular analysis of the 5q-syndrome
Autor: Boultwood, J
Vydáno: (2007)

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.
Autor: Barlow, J, a další
Vydáno: (2010)

Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes.
Autor: Fernandez-Mercado, M, a další
Vydáno: (2013)

Combined immunophenotyping and FISH identifies the involvement of B-cells in 5q- syndrome.
Autor: Jaju, R, a další
Vydáno: (2000)

Activation of the mTOR signaling pathway by L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.
Autor: Yip, B, a další
Vydáno: (2013)

NRAS, FLT3 and TP53 mutations in patients with myelodysplastic syndrome and a del(5q).
Autor: Fidler, C, a další
Vydáno: (2004)

Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression
Autor: Martin Jädersten, a další
Vydáno: (2009-12-01)

Activation of the mTOR signaling pathway by L-leucine in 5q-syndrome and other RPS14-deficient erythroblasts
Autor: Yip, B, a další
Vydáno: (2013)

Narrowing and genomic annotation of the commonly deleted region of the 5q- syndrome.
Autor: Boultwood, J, a další
Vydáno: (2002)

Allelic loss of IRF1 in myelodysplasia and acute myeloid leukemia: retention of IRF1 on the 5q- chromosome in some patients with the 5q- syndrome.
Autor: Boultwood, J, a další
Vydáno: (1993)

Lenalidomide up-regulates SPARC and inhibits in vitro growth of the malignant clone in myelodysplastic syndrome patients with 5q deletion.
Autor: Pellagatti, A, a další
Vydáno: (2006)

Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients.
Autor: Pellagatti, A, a další
Vydáno: (2007)