Advances in the 5q- syndrome.

Advances in the 5q- syndrome.

The 5q- syndrome is the most distinct of all the myelodysplastic syndromes with a clear genotype/phenotype relationship. The significant progress made during recent years has been based on the determination of the commonly deleted region and the demonstration of haploinsufficiency for the ribosomal...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Boultwood, J, Pellagatti, A, McKenzie, A, Wainscoat, J
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2010

Ижил төстэй зүйлс

5q- syndrome.
-н: Boultwood, J, зэрэг
Хэвлэсэн: (2012)

RECENT ADVANCES IN THE 5Q- SYNDROME
-н: Andrea Pellagatti, зэрэг
Хэвлэсэн: (2015-05-01)

Haploinsufficiency of ribosomal proteins and p53 activation in anemia: Diamond-Blackfan anemia and the 5q- syndrome.
-н: Boultwood, J, зэрэг
Хэвлэсэн: (2012)

The 5q-syndrome.
-н: Boultwood, J, зэрэг
Хэвлэсэн: (1994)

Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome.
-н: Pellagatti, A, зэрэг
Хэвлэсэн: (2010)

Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies.
-н: Boultwood, J, зэрэг
Хэвлэсэн: (2013)

The 5q- syndrome.
-н: Giagounidis, A, зэрэг
Хэвлэсэн: (2004)

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome.
-н: Pellagatti, A, зэрэг
Хэвлэсэн: (2011)

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome
-н: Pellagatti, A, зэрэг
Хэвлэсэн: (2011)

Gene expression profiling in 5q-syndrome and myelodysplastic syndromes.
-н: Pellagatti, A, зэрэг
Хэвлэсэн: (2003)

MOLECULAR DELINEATION OF THE CRITICAL REGION OF THE 5Q-CHROMOSOME IN THE 5Q-SYNDROME
-н: Boultwood, J, зэрэг
Хэвлэсэн: (1993)

The human POP2 gene: identification, sequencing, and mapping to the critical region of the 5q- syndrome.
-н: Fidler, C, зэрэг
Хэвлэсэн: (1999)

Expression profiling of CD34+cells in patients with myelodysplastic syndromes with and without a del(5q)
-н: Pellagatti, A, зэрэг
Хэвлэсэн: (2005)

Lenalidomide selectively inhibits in vitro growth of the malignant clone in myelodysplastic syndrome (MDS) patients with 5q deletion.
-н: Jadersten, M, зэрэг
Хэвлэсэн: (2005)

Gene expression profiling in the myelodysplastic syndromes.
-н: Pellagatti, A, зэрэг
Хэвлэсэн: (2005)

Molecular mapping of uncharacteristically small 5q deletions in two patients with the 5q- syndrome: delineation of the critical region on 5q and identification of a 5q- breakpoint.
-н: Boultwood, J, зэрэг
Хэвлэсэн: (1994)

MOLECULAR MAPPING OF UNCHARACTERISTICALLY SMALL 5Q DELETIONS IN 2 PATIENTS WITH THE 5Q- SYNDROME - DELINEATION OF THE CRITICAL REGION ON 5Q AND IDENTIFICATION OF A 5Q- BREAKPOINT
-н: Boultwood, J, зэрэг
Хэвлэсэн: (1993)

Effects of L-leucine in 5q-syndrome and other RPS14-deficient erythroblasts
-н: Yip, B, зэрэг
Хэвлэсэн: (2012)

Effects of L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.
-н: Yip, B, зэрэг
Хэвлэсэн: (2012)

Expression profiling of CD34+cells in patients with myelodysplastic syndromes with and without a del(5q).
-н: Pellagatti, A, зэрэг
Хэвлэсэн: (2004)

Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression.
-н: Jädersten, M, зэрэг
Хэвлэсэн: (2009)

SF3B1 mutant myelodysplastic syndrome: Recent advances
-н: Pellagatti, A, зэрэг
Хэвлэсэн: (2020)

ISOLATION OF NOVEL CDNA CLONES MAPPING TO THE CRITICAL REGION OF THE 5Q-CHROMOSOME IN THE 5Q-SYNDROME
-н: Boultwood, J, зэрэг
Хэвлэсэн: (1994)

Homozygous deletion of FMS in a patient with the 5q- syndrome.
-н: Boultwood, J, зэрэг
Хэвлэсэн: (1990)

Narrowing and genomic annotation of the critical region of the 5q-syndrome.
-н: Boultwood, J, зэрэг
Хэвлэсэн: (2000)

Gene expression profiling of CD34+ cells in patients with the 5q- syndrome.
-н: Boultwood, J, зэрэг
Хэвлэсэн: (2007)

Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes.
-н: Pellagatti, A, зэрэг
Хэвлэсэн: (2008)

Physical mapping of the human ATX1 homologue (HAH1) to the critical region of the 5q- syndrome within 5q32, and immediately adjacent to the SPARC gene.
-н: Boultwood, J, зэрэг
Хэвлэсэн: (2000)

Molecular analysis of the 5q-syndrome
-н: Boultwood, J
Хэвлэсэн: (2007)

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.
-н: Barlow, J, зэрэг
Хэвлэсэн: (2010)

Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes.
-н: Fernandez-Mercado, M, зэрэг
Хэвлэсэн: (2013)

Combined immunophenotyping and FISH identifies the involvement of B-cells in 5q- syndrome.
-н: Jaju, R, зэрэг
Хэвлэсэн: (2000)

Activation of the mTOR signaling pathway by L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.
-н: Yip, B, зэрэг
Хэвлэсэн: (2013)

NRAS, FLT3 and TP53 mutations in patients with myelodysplastic syndrome and a del(5q).
-н: Fidler, C, зэрэг
Хэвлэсэн: (2004)

Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression
-н: Martin Jädersten, зэрэг
Хэвлэсэн: (2009-12-01)

Activation of the mTOR signaling pathway by L-leucine in 5q-syndrome and other RPS14-deficient erythroblasts
-н: Yip, B, зэрэг
Хэвлэсэн: (2013)

Narrowing and genomic annotation of the commonly deleted region of the 5q- syndrome.
-н: Boultwood, J, зэрэг
Хэвлэсэн: (2002)

Allelic loss of IRF1 in myelodysplasia and acute myeloid leukemia: retention of IRF1 on the 5q- chromosome in some patients with the 5q- syndrome.
-н: Boultwood, J, зэрэг
Хэвлэсэн: (1993)

Lenalidomide up-regulates SPARC and inhibits in vitro growth of the malignant clone in myelodysplastic syndrome patients with 5q deletion.
-н: Pellagatti, A, зэрэг
Хэвлэсэн: (2006)

Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients.
-н: Pellagatti, A, зэрэг
Хэвлэсэн: (2007)