Analysis of two-dimensional dissociation constant of laterally mobile cell adhesion molecules.

We formulate a general analysis to determine the two-dimensional dissociation constant (2D Kd), and use this method to study the interaction of CD2-expressing T cells with glass-supported planar bilayers containing fluorescently labeled CD58, a CD2 counter-receptor. Both CD2 and CD58 are laterally m...

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Bibliographic Details
Main Authors: Zhu, D, Dustin, M, Cairo, C, Golan, D
Format: Journal article
Language:English
Published: 2007