Liberty asthma QUEST: Phase 3 randomized, double-blind, placebo-controlled, parallel-group study to evaluate dupilumab efficacy/safety in patients with uncontrolled, moderate-to-severe asthma

<h4>Introduction</h4> <p>Dupilumab, a fully human anti-IL-4Ra monoclonal antibody, inhibits signaling of both interleukin (IL)-4 and IL-13, which are key drivers of type 2-mediated inflammation. Dupilumab is approved in the EU, USA, and other countries for the treatment of adults...

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Bibliographic Details
Main Authors: Busse, WW, Maspero, JF, Rabe, KF, Papi, A, Wenzel, SE, Ford, LB, Pavord, ID, Zhang, B, Staudinger, H, Pirozzi, G, Amin, N, Akinlade, B, Eckert, L, Chao, J, Graham, NMH, Teper, A
Format: Journal article
Language:English
Published: Springer 2018