Harnessing FOXP3+ regulatory T cells for transplantation tolerance.
Early demonstrations that mice could be tolerized to transplanted tissues with short courses of immunosuppressive therapy and that with regard to tolerance to self, CD4+FOXP3+ regulatory T cells (Tregs) appeared to play a critical role, have catalyzed strategies to harness FOXP3-dependent processes...
Autori principali: | Waldmann, H, Hilbrands, R, Howie, D, Cobbold, S |
---|---|
Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
American Society for Clinical Investigation
2014
|
Documenti analoghi
Documenti analoghi
-
Regulatory T cells and transplantation tolerance.
di: Hilbrands, R, et al.
Pubblicazione: (2013) -
Regulatory T cells and transplantation tolerance
di: Hilbrands, R, et al.
Pubblicazione: (2013) -
Induced Foxp3+ T cells colonising tolerated allografts exhibit the hypomethylation pattern typical of mature regulatory T cells
di: Howie, D, et al.
Pubblicazione: (2016) -
Sustained suppression by Foxp3+ regulatory T cells is vital for infectious transplantation tolerance.
di: Kendal, A, et al.
Pubblicazione: (2011) -
The induction of transplantation tissue tolerance requires Foxp3 expression
di: Regateiro, F, et al.
Pubblicazione: (2013)