Identification and functional characterization of cytoplasmic determinants of plasmid DNA nuclear import.

Import of exogenous plasmid DNA (pDNA) into mammalian cell nuclei represents a key intracellular obstacle to efficient non-viral gene delivery. This includes access of the pDNA to the nuclei of non-dividing cells where the presence of an intact nuclear membrane is limiting for gene transfer. Here we...

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Bibliographic Details
Main Authors:	Munkonge, F, Amin, V, Hyde, S, Green, A, Pringle, I, Gill, DR, Smith, J, Hooley, R, Xenariou, S, Ward, M, Leeds, N, Leung, K, Chan, M, Hillery, E, Geddes, D, Griesenbach, U, Postel, E, Dean, D, Dunn, M, Alton, E
Format:	Journal article
Language:	English
Published:	2009

Identification and functional characterization of cytoplasmic determinants of plasmid DNA nuclear import.

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