Rapid collapse and slow structural reorganisation during the refolding of bovine alpha-lactalbumin.

The refolding of bovine alpha-lactalbumin (BLA) from its chemically denatured state in 6 M GuHCl has been investigated by a variety of complementary biophysical approaches. CD experiments indicate that the species formed in the early stages of refolding of the apo-protein have at least 85 % of the a...

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Detalles Bibliográficos
Autores principales: Forge, V, Wijesinha, RT, Balbach, J, Brew, K, Robinson, C, Redfield, C, Dobson, C
Formato: Journal article
Lenguaje:English
Publicado: 1999