Mature CD8(+) T lymphocyte response to viral infection during fetal life.

Immunization of newborns against viral infections may be hampered by ineffective CD8(+) T cell responses. To characterize the function of CD8(+) T lymphocytes in early life, we studied newborns with congenital human cytomegalovirus (HCMV) infection. We demonstrate that HCMV infection in utero leads...

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Bibliographic Details
Main Authors: Marchant, A, Appay, V, Van Der Sande, M, Dulphy, N, Liesnard, C, Kidd, M, Kaye, S, Ojuola, O, Gillespie, G, Vargas Cuero, A, Cerundolo, V, Callan, M, McAdam, K, Rowland-Jones, S, Donner, C, Mcmichael, A, Whittle, H
Format: Journal article
Language:English
Published: 2003