Localised translation of gurken/TGF-α mRNA during axis specification is controlled by access to Orb/CPEB on Processing bodies

In Drosophila oocytes, gurken/TGF-α mRNA is essential for establishing the future embryonic axes. gurken remains translationally silent during transport from its point of synthesis in nurse cells to its final destination in the oocyte, where it associates with the edge of Processing bodies. Here, we...

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Detalhes bibliográficos
Principais autores: Davidson, A, Parton, R, Rabouille, C, Weil, T, Davis, I
Formato: Journal article
Publicado em: Cell Press 2016