How much fat is necessary to optimize lumefantrine oral bioavailability?
BACKGROUND: Artemether-lumefantrine (AL) is the only fixed, artemisinin-based combination antimalarial drug which is registered internationally and deployed on a large scale. Absorption of the hydrophobic lipophilic lumefantrine component varies widely between individuals and is greatly increased b...
Главные авторы: | , , , , , , , , |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
2007
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