How much fat is necessary to optimize lumefantrine oral bioavailability?

BACKGROUND: Artemether-lumefantrine (AL) is the only fixed, artemisinin-based combination antimalarial drug which is registered internationally and deployed on a large scale. Absorption of the hydrophobic lipophilic lumefantrine component varies widely between individuals and is greatly increased b...

Полное описание

Библиографические подробности
Главные авторы: Ashley, E, Stepniewska, K, Lindegårdh, N, Annerberg, A, Kham, A, Brockman, A, Singhasivanon, P, White, N, Nosten, F
Формат: Journal article
Язык:English
Опубликовано: 2007