Thalamocortical development: how are we going to get there?
The arealization of the mammalian cortex is believed to be controlled by a combination of intrinsic factors that are expressed in the cortex, and external signals, some of which are mediated through thalamic input. Recent studies on transgenic mice have identified families of molecules that are invo...
| Autori principali: | , |
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| Natura: | Journal article |
| Lingua: | English |
| Pubblicazione: |
2003
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| _version_ | 1826270619094745088 |
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| author | López-Bendito, G Molnár, Z |
| author_facet | López-Bendito, G Molnár, Z |
| author_sort | López-Bendito, G |
| collection | OXFORD |
| description | The arealization of the mammalian cortex is believed to be controlled by a combination of intrinsic factors that are expressed in the cortex, and external signals, some of which are mediated through thalamic input. Recent studies on transgenic mice have identified families of molecules that are involved in thalamic axon growth, pathfinding and cortical target selection, and we are beginning to understand how thalamic projections impose cytoarchitectonic differentiation on the developing cortex. By unravelling these mechanisms further, we should be able to increase our understanding of the principles of cortical organization. |
| first_indexed | 2024-03-06T21:43:41Z |
| format | Journal article |
| id | oxford-uuid:48cfaca2-3119-4c9e-8db9-44a3723254e3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:43:41Z |
| publishDate | 2003 |
| record_format | dspace |
| spelling | oxford-uuid:48cfaca2-3119-4c9e-8db9-44a3723254e32022-03-26T15:27:55ZThalamocortical development: how are we going to get there?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:48cfaca2-3119-4c9e-8db9-44a3723254e3EnglishSymplectic Elements at Oxford2003López-Bendito, GMolnár, ZThe arealization of the mammalian cortex is believed to be controlled by a combination of intrinsic factors that are expressed in the cortex, and external signals, some of which are mediated through thalamic input. Recent studies on transgenic mice have identified families of molecules that are involved in thalamic axon growth, pathfinding and cortical target selection, and we are beginning to understand how thalamic projections impose cytoarchitectonic differentiation on the developing cortex. By unravelling these mechanisms further, we should be able to increase our understanding of the principles of cortical organization. |
| spellingShingle | López-Bendito, G Molnár, Z Thalamocortical development: how are we going to get there? |
| title | Thalamocortical development: how are we going to get there? |
| title_full | Thalamocortical development: how are we going to get there? |
| title_fullStr | Thalamocortical development: how are we going to get there? |
| title_full_unstemmed | Thalamocortical development: how are we going to get there? |
| title_short | Thalamocortical development: how are we going to get there? |
| title_sort | thalamocortical development how are we going to get there |
| work_keys_str_mv | AT lopezbenditog thalamocorticaldevelopmenthowarewegoingtogetthere AT molnarz thalamocorticaldevelopmenthowarewegoingtogetthere |