Clinical and biological implications of driver mutations in myelodysplastic syndromes.

Myelodysplastic syndromes (MDS) are a heterogeneous group of chronic hematological malignancies characterized by dysplasia, ineffective hematopoiesis and a variable risk of progression to acute myeloid leukemia. Sequencing of MDS genomes has identified mutations in genes implicated in RNA splicing,...

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Bibliografski detalji
Glavni autori:	Papaemmanuil, E, Gerstung, M, Malcovati, L, Tauro, S, Gundem, G, Van Loo, P, Yoon, C, Ellis, P, Wedge, D, Pellagatti, A, Shlien, A, Groves, M, Forbes, SA, Raine, K, Hinton, J, Mudie, L, McLaren, S, Hardy, C, Latimer, C, Della Porta, MG, O'Meara, S, Ambaglio, I, Galli, A, Butler, A, Walldin, G
Format:	Journal article
Jezik:	English
Izdano:	2013

Clinical and biological implications of driver mutations in myelodysplastic syndromes.

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