Clinical and biological implications of driver mutations in myelodysplastic syndromes.

Myelodysplastic syndromes (MDS) are a heterogeneous group of chronic hematological malignancies characterized by dysplasia, ineffective hematopoiesis and a variable risk of progression to acute myeloid leukemia. Sequencing of MDS genomes has identified mutations in genes implicated in RNA splicing,...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Papaemmanuil, E, Gerstung, M, Malcovati, L, Tauro, S, Gundem, G, Van Loo, P, Yoon, C, Ellis, P, Wedge, D, Pellagatti, A, Shlien, A, Groves, M, Forbes, SA, Raine, K, Hinton, J, Mudie, L, McLaren, S, Hardy, C, Latimer, C, Della Porta, MG, O'Meara, S, Ambaglio, I, Galli, A, Butler, A, Walldin, G
Format: Journal article
Język:English
Wydane: 2013