The association of HLA DR beta alleles with self-limiting and persistent forms of early symmetrical polyarthritis.

RA is associated with a group of class II DR beta alleles, which share a conserved sequence in the third allelic hypervariable region (3AHVR). These include the DR4 subtypes Dw4, Dw14 and Dw15, and also DR1. In contrast Dw10 and Dw13 which are also DR4 subtypes show no association with RA and have a...

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Bibliographic Details
Main Authors: Salmon, M, Wordsworth, P, Emery, P, Tunn, E, Bacon, P, Bell, J
Format: Journal article
Language:English
Published: 1993